Diabetes Ketoacidosis (DKA) – Pathophysiology
In this video I have the pathophysiology of diabetes ketoacidosis seen primarily in type 1 diabetes mellitus. Absolute deficiency of insulin leads to increase in glucagon and decreased peripheral utilization of glucose leading to increased blood glucose level. Increased glucagon along with catecholamines and cortisol leads to increased gluconeogenesis thereby outpouring of glucose from liver into blood which increases blood glucose level. Increased lipolysis leads to increased free fatty acids leading to increased generation of ketone bodies. Increased ketone bodies like acetoacetate and beta-hydroxybutyrate in the blood lead to decrease in blood pH leading to metabolic acidosis.
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Thank you very much doctor
Sir it was a nice explanation.
Thank.you.very.much.sir.
thanks doctor
Thank you
Sir g agger insulin injections se suger normal hu to pir insulin Chor sakte hu
agar ap regular insulin user hain to nahi chor sakte i am a diabetic too if u need any help feel free to contact zero three four seven three seven double eight seven double nine
hindi men bol dete bhai
Always a great review 🙂 Thank you Dr. Mungli
Thank you Michael ?? nice to hear from you
Fantastic video doctor, god bless you
Thank you sir?