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Diabetes 21, Diabetic neuropathy

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Neuropathy
Part of the cause of diabetic peripheral neuropathy is damage to the Schwann cells which form the myelin sheath around peripheral nerves. Schwann cell damage probably occurs for metabolic reasons and can lead to areas of demyelination. As part of the function of Schwann cells is to protect and nourish the nerve fibres there will be progressive fibre degeneration. In peripheral nerves the microvascular changes already described are likely to be an additional factor in the development of peripheral neuropathy. Ischaemia of peripheral nerves will lead to hypoxic damage as neurones are very sensitive to oxygen lack. Evidence for this comes from the fact that unmyelinated nerve fibres are affected as well as the myelinated fibres. Initially there will be shrinkage of axons followed by fragmentation. Neuropathy can lead to sensory and motor deficiency in the legs and often presents with tingling and numbness. Sensory neuropathy is the most common presentation resulting is reduced sensation and pain awareness from the feet. This can result in the patient being unaware of developing injuries to the feet. Bladder problems and impotence may also be caused by peripheral nerve defects.

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42 comments

  1. Zacrist Tfm

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    1. parridit nadia

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    2. SUGU SEBATTI

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    3. jesus lopez

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    4. Jesús Manuel Graterol Toro

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  2. My work Channel

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  3. Hayrdnell Cayaspo

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    1. Isaias Medina

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  4. Radomir Tesic

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    1. Lucas Gabriel

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    1. Ajna Su

      Great Video clip! Excuse me for the intrusion, I would love your initial thoughts. Have you considered – Taparton Sturdy Nerves Takeover (should be on google have a look)? It is a great one off guide for Getting rid of Neuropathy minus the hard work. Ive heard some unbelievable things about it and my BF after a lifetime of fighting got excellent results with it.

    2. Jose F. Torrealba

      I certainly accept what a couple of others said – it’s not as easy than some people make out to find a natural remedy for neuropathy.
      Be careful and take advice from other people. I looked many websites and discovered plenty of good advice by searching google on sites like Gabs Neuro Guide. Good luck and hope you succeed!

  5. David Lawrie

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    1. Petar Petrovic

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    2. J StapletonV

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    1. md Monowar

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    2. trollaccount

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    1. yaa agyekum

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  6. Igor Sidelkovsky

    I agree with a few other comments said – it’s not straight forward than it sounds to treat neuropathy at home.
    Be cautious and take advice from experts. I looked round many websites and discovered a lot of great advice by searching google on websites such as Gabs Neuro Guide. I wish you luck and hope you are successful!

    1. Kyle Ashler

      Lovely video content! Forgive me for butting in, I would love your thoughts. Have you thought about – Taparton Sturdy Nerves Takeover (should be on google have a look)? It is an awesome one of a kind product for Getting rid of Neuropathy minus the headache. Ive heard some amazing things about it and my old buddy Taylor got cool success with it.

    1. Emprendiendo en tiempos de coronavirus

      Kudos for the video content! Forgive me for chiming in, I would appreciate your opinion. Have you thought about – Taparton Sturdy Nerves Takeover (do a google search)? It is an awesome exclusive guide for Getting rid of Neuropathy without the hard work. Ive heard some decent things about it and my close friend Aubrey at very last got great success with it.

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